Mystery Slide Sessions
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Solve the Mystery!

Get ready for to review the Mystery Slides! Links to the neuropathology and muscle pathology mystery slides are below.

Give us your best guess on the mystery cases for the Neuropathology and Muscle Pathology sessions.  Connect to the google sheet below to log in your answers. Those logging in to guess will receive a complimentary beverage ticket for the session!  

Sunday, November 4, 2018
7:30 p.m.-9:30 p.m.
Thurgood Ballroom West, Exhibition Lower Level, Marriott Wardman Park Hotel
Mystery Slide Review Session: Neuropathology
Session Chair:
Andrew DMillerDVM, DACVPCornell UniversityIthaca, NY

Link to Neuropathology Slides

Enter your best guess here for the neuropathology mystery slides! 


Case 1:  Tissue from an 8-year-old spayed female dog with a three month history of progressive vision loss and one month history of circling to the left.  

Case 2:  Tissue from an 8-year-old female neutered Bulldog with a two month history of abnormal mentation and behavior (sporadic vocalization) progressing to generalized seizure activity with mild obtundation.  A mass was noted in the right medial retropharyngeal lymph node.

 Case 3:  Tissue from a 9-year-old Thomson’s gazelle (Eudorcas thomsonii) with a one week history of neurologic signs that began with circling and lethargy, which progressed to ataxia and eventual recumbency. 

Case 4:  Tissue from a 9-month-old spayed female mixed breed dog with a history of progressive paresis since birth, starting in the hind limbs and progressing to all limbs. 

Case 5:  Tissue from a 7-week-old male Gloucestershire Old Spots (GOS) mix piglet with a history of swollen lymph nodes and severe coughing fits.  

Case 6:  Tissues from two, 5-week-old piglets submitted from a herd that was struggling with respiratory disease following placement into nursery/grower facilities. One pig was reported to have been down on one side and paddling with its legs while the other pig displayed exaggerated and uncoordinated movements.  

Case 7:  Tissue from a 3-week-old Angus cross with a two-week history of progressive neurologic signs including circling, head pressing, laying down often, and having trouble rising.  

Case 8:  Tissue from a 2-year-old Angolan Colobus monkey (Colobus angolensis palliates) that was found obtunded and ataxic on neurologic examination.  

Case 9:  A 9-year-old castrated male domestic short-haired cat exhibited acute onset paralysis of four limbs.  



 Monday, November 5, 2018

7:00 p.m.-9:00 p.m.

Thurgood Ballroom West, Mezzanine Level, Marriott Wardman Park Hotel
Mystery Slide Review Session: Muscle Pathology
Session Chairs: 
G. Diane Shelton, DVM, PhD, DACVIM, University of California, San Diego, CA
Heather Tillman, DVM, PhD, DACVP, St. Jude Children’s Research Hospital, Memphis, TN


Link to Muscle Pathology Slides

Enter your best guess here for the muscle pathology mystery slides! 


Case 1. Skeletal muscle and heart tissue from a 13-year-old MC Maine Coon cat. The cat was diagnosed with mycobacteriosis 5 years previously and treated over the ensuing 5 years. Euthanasia was performed following a period of clinical decline. 

Case 2. Skeletal muscle biopsy from a 7-year-old Dutch warmblood gelding horse. The horse had an approximately 8-month history of lameness that was unresponsive to rehabilitation. A pelvic sacroiliac joint injury was suspected.

Case 3. Skeletal muscle tissue from a bovine heifer of unknown age collected at necropsy. No clinical history was available.

Case 4. Muscle tissue from a 3.5-year-old captive-bred female Panamanian golden frog housed at the Maryland Zoo in Baltimore. The frog presented with signs of weight loss, skin discoloration and pelvic limb tetany. 

Case 5. Skeletal muscle tissue collected at necropsy from an 8-day-old Quarter horse filly with a one-day history of weakness that progressed to recumbency during hospitalization. 

Case 6. Muscle tissue obtained at necropsy from a 1-month-old Gypsy Vanner/Saddlebred cross foal. The foal was found dead approximately 2 hours after the initial observation of lethargy and rapid breathing. 

Case 7. Muscle tissue from a 3-month-old genetically engineered mutation in a mouse model. Small stature and progressive gait abnormalities were present. 


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