The Jackson Laboratory
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Organization/Company: The Jackson Laboratory

Location: Bar Harbor, ME USA


Pathology Environment: Academic Laboratory

Discipline/Field of Study: See below

Length of Externship: One month minimum

Time of Year: Anytime

Funding: No

Housing Provided: Provided by Dr. Sundberg

Description of Externship:

The Jackson Laboratory is a private, non-profit research institution that focuses on basic research using laboratory mice as a biomedical tool. Our institution is located on Mount Desert Island and is surrounded by Acadia National Park. I offer opportunities for veterinary students, pathology residents, and scientists at all stages of their career to work in my basic science research laboratory. I require a minimum of one month. Visiting investigators take part in ongoing research dealing with genetic based skin diseases in laboratory mice. We are identifying mutated genes associated with skin, hair, and nail disorders in simple Mendelian genetic models (one gene) or complex polygenic traits that result in disease. Many of the current projects deal with validating rare genetic variants in human patients by creating mice carrying the same mutation using CRISPR/Cas9. The projects vary constantly depending on funding. We currently are working on alopecia areata, scaly skin diseases (psoriasis, ichthyosis and palmoplantar keratoderma-like diseases), blistering skin diseases (several forms of epidermolysis bullosa), and diseases characterized by ectopic mineralization (pseudoxanthoma elasticum). The Jackson Laboratory has reasonably priced short term housing options ranging from rooms in houses next to campus to summer cottages to accommodate families of visiting scientists. Mentorship grants are available for up to $3000 from the American Hair Research Society. However, these are competitive and need to be applied for by November each fall and are not available until the following March. These grants cover travel, room, and board. Other funding opportunities are available from additional foundations depending on the topic and competitive applications. Due to the large number of applicants, I recommend contacting me early, preferably two years in advance. Visits can be coordinated so that you can participate in our annual course, Pathology of Mouse Models of Human Diseases (when it is held at The Jackson Laboratory) which is one week long each fall.    

Dr. John Sundberg, Professor
The Jackson Laboratory
600 Main St.
Bar Harbor, ME 04609 




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