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2005 Toxicologic Pathology Platform and Posters
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Sunday, December 4, 2005

Toxicologic Pathology Specialty Group Session I
(Vet. Path. Abstracts 185-188)

Chair:  D.B. Tumas
Committee Members: A.Provencher-Bolliger, B.D. Car, D.L. Hutto, M.W. Leach, L. Tomlinson

Platform Presentations:

1:30 p.m. – 1:40 p.m.
OPENING REMARKS

1:40 p.m. – 2:40 p.m.
Invited Speaker
PATHOBIOLOGY IN THE MMP AND ADAM FAMILIES     DETERMINED BY INDUCED MUTATIONS
J.C.L. Schuh
Keyword: Toxicologic Pathology, Abstract number 185

2:40 p.m. – 3:00 p.m.
ORAL AND ESOPHAGEAL PATHOLOGY IN BALB/C MICE FOLLOWING CHRONIC ADMINISTRATION OF TGF-BETA ANTAGONIST
A. Vitsky, R. Pawliuk, E. LaCasse, M. Huff, S. Ryan, L. Andrews, C. Nelson, J. Tedstone, R. D. Garman, M. C. Ruzek, M. Hawes, and B. L. Thurberg,
Keyword: Alimentary, Abstract Number 186

3:00 p.m. - 3:30 p.m.
REFRESHMENT BREAK - VISIT THE POSTERS AND EXHIBITS!

3:30 p.m. – 3:50 p.m.
PHYTOL-INDUCED HEPATOTOXICITY IN MICE: IMPLICATIONS FOR PEROXISOMAL OXIDATION OF LIPIDS.
J.T. Mackie, B.P. Atshaves, H.R. Payne, A.L. McIntosh, F. Schroeder, and A.B. Kier.
Keyword: Liver and Pancreas, Abstract Number 187

3:50 p.m. – 4:50 p.m.
Invited Speaker
EVALUATING MECHANISM-BASED TOXICITY OF TACE INHIBITORS
L. Lehman-McKeeman

4:50 p.m. – 5:10 p.m.
INVESTIGATION OF BIOMARKERS AND MECHANISMS OF P-AMINOPHENOL-INDUCED NEPHROTOXICITYA. H. Yang, C. Fuentealba, B. Jessen, and O. Illanes
Keyword: Toxicologic Pathology, Abstract Number 188


Tuesday, December 6, 2005

Toxicologic Pathology Specialty Group Session II
(Vet. Path. Abstracts 189-199)

Chair:  D.B. Tumas
Committee Members: A.Provencher-Bolliger, B.D. Car, D.L. Hutto, M.W. Leach, L. Tomlinson

Platform Presentations

1:30 p.m. – 1:40 p.m.
OPENING REMARKS

1:40 p.m. – 2:40 p.m.
Invited Speaker
MMPS IN HEALTH AND DISEASE: LESSONS FROM GENE TARGETED MICE
S.D. Shapiro

2:40 p.m. – 3:00 p.m.
ANTI-RAT ERBB2 ACCELERATES DOXORUBICIN CARDIAC TOXICITY IN RATS
K. Gabrielson, N. Muratore, S. Pin, and D. Bedja
Keyword: Toxicologic Pathology, Abstract Number 189

3:00 p.m. - 3:30 p.m.
REFRESHMENT BREAK - VISIT THE POSTERS AND EXHIBITS!

3:30 p.m. – 3:50 p.m.
ANDROGEN DEPENDENT MAMMARY GLAND VIRILISM IN RATS GIVEN A SELECTIVE ESTROGEN RECEPTOR MODULATOR (SERM)
D.G. Rudmann, I.R. Cohen, M.R. Robbins, D.E. Coutant, and J.W. Henck
Keyword: Reproductive System, Abstract Number 190

3:50 p.m. – 4:45 p.m.
Invited Speaker
SKELETAL CHANGES ASSOCIATED WITH MMP INHIBITORS
D. Gunson

4:45 p.m. – 5:00 p.m.
COMPREHENSIVE GENE PROFILING OF THE LIVER IN A LIEBER DECARLI RAT MODEL TO PREDICT PROGRESSION TO ALCOHOLIC STEATOHEPATITIS
S.K. Ramaiah, A. Banerjee, R. Pettway, and A. Jayaraman Keyword: Toxicologic Pathology, Abstract Number 191

Poster Presentations:

T-1

EARLY ONSET OF SPONTANEOUS RENAL TUBULAR ADENOMA AND MAMMARY GLAND ADENOCARCINOMA IN YOUNG SPRAGUE-DAWLEY RATS (RATTUS NORVEGICUS).
C. Savard, W.I. Anderson, D.B. Walker, and A.J. Lambert
Keyword: Mammary, Abstract Number 192

T-2

LIVER LESIONS IN CATTLE EXPERIMENTALLY POISONED BY SENECIO BRASILIENSIS: QUANTITATIVE AND SEMI-QUANTITATIVE STUDY OF EXTRACELLULAR MATRIX AND SINUSOIDAL CELLS
M. Torres, K. Coelho, and A. Biondo
Keyword: Toxicologic Pathology, Abstract Number 193

T-3

INCIDENCE OF SPONTANEOUS MYOCARDIAL VALVULAR LESIONS IN RATS AND MICE ON SUB-CHRONIC AND CHRONIC TOXICITY STUDIES
J. E. Stewart, A.S. Howells, and W.I. Anderson
Keyword: Cardiovascular, Abstract Number 194

T-4#

PATHWAY OF P53-DEPENDENT TROPHOBLAST CELL APOPTOSIS IN CYTOSINE ARABINOSIDE-TREATED PLACENTA
H. Yamauchi, K. Katayama, M. Ueno, K. Uetsuka, H. Nakayama, and K. Doi
Keyword: Reproductive System, Abstract 195

T-5

EFFECTS OF PREGNANCY AND LACTATION ON CYPs PROTEIN AND GENE EXPRESSION PROFILING DURING PREGNANCY IN RAT LIVER
X.J. He, N. Ejiri, H. Yamauchi, H. Nakayama, and K. Doi
Keyword: Liver and Pancreas, Abstract Number 196

T-6

DEFINING THE SAFETY OF DRUG-ELUTING STENTS SYSTEMS IN PORCINE CORONARY AND RABBIT ILIAC ARTERIAL MODELS
L. Perkins and L. Coleman
Keyword: Cardiovascular, Abstract Number 197

T-7

EVALUATION OF THE EFFECT OF A VEGFR-2 INHIBITOR ON ALANINE AMINOTRANSFERASE GENE EXPRESSION AND CONCENTRATION IN THE RAT LIVER
M. Bera, W. Evering, C. Fuentealba, B. Jessen, F. Sace, G. Stevens, D. Trajkovic, and A. Yang
Keyword: Liver and Pancreas, Abstract Number 198

T-8

ADVANCING THE STATE-OF-THE-SCIENCE OF IMMUNOTOXICOLOGY
C.J. Faherty
Keyword: Immune System, Abstract Number 199

#Competitor for the ACVP Young Investigator Award

##Competitor for the 2005 Christopher T. Starost Memorial Oncology Award

 

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