Allergan is a global, technology-driven multi-specialty health care company pursuing therapeutic advances to help patients live life to their fullest potential. In making this commitment, we work to develop an unparalleled level of insight into patients' wants and needs — and into the priorities and concerns of the medical specialists who treat them. To this end, we employ more than 50 percent of our work force in either research and development (R&D) or sales, ensuring our efforts are focused on innovation and our customers.

The Opportunity:

• Provides scientific and technical expertise in experimental and toxicologic pathology within Drug Safety Evaluation.  As pathology representative helps design, conduct and interpret in-house and CRO toxicology studies to support Discovery, Pre-Development and Development.  Supervises conduct of in-house necropsy and integrates pharmacologic, in-life, organ weight, clinical pathologic toxicokinetic and macroscopic data with microscopic findings in in-house toxicology reports.  Peer reviews pathology data for in-house reports.  Serves as pathology monitor at CROs, including protocol review, pathology peer review and report review.  Implements innovative pathology-based approaches and techniques to solve issues of toxicological concern.  Provides investigative pathology support to Discovery Programs.  Stays abreast of current literature and trends.  Accomplished in working under SOPs in a GLP environment.
• Provides pathology support for Development projects.  Designs and reviews nonclinical protocols based on scientific rationale and/or regulatory guidelines. Supervises conduct of in house necropsy or serves as pathology monitor for CRO studies.  Conducts anatomic and clinical pathological and organ weight evaluation and ensures integration of this data with pharmacologic, in-life, toxicokinetic and macroscopic data in discussion/conclusions.  Coauthors in house reports and reviews CRO reports with pathology data Conducts pathology peer reviews of in-house and CRO studies. Reviews relevant literature and background information.
• Provides pathology support for Discovery and/or investigative programs to address target organ toxicity.  Participates in designing, reviewing and approving nonclinical protocols.  Conducts anatomic pathological evaluation using standard and/or investigative methodology and integrates this data with relevant ancillary data for compound lead selection or investigative evaluation.
• Represents the Pathology Department on various project/program teams by discussing, contributing to, and reviewing programs, projects and by advising teams and management on timings of completed tasks, important findings and decision making. Participates in review of regulatory and clinical documents regarding nonclinical safety data and human dose setting or risk assessment.  Informs management of ongoing and planned project/program activities and potential issues or conflicts.  Responds to regulatory or clinical inquiries.
• Supports departmental objectives by improving existing procedures and practices and introduction of enhanced capabilities.  Provides input to staff guidance and training to increase knowledge and skill base.  Writes or reviews and revises standard operating procedures and guidelines.
• Maintains up-to-date knowledge and/or technical advances in the fields of pathology, toxicology, and related disciplines and therapeutic areas, Good Laboratory Practices, and veterinary and laboratory animal science.  Benchmarking for industry standards. Cultivation of personal research interests.  Contribute to internal and external scientific presentations.  Development of productive internal collaborations.  Active participation in professional societies.

The Requirements:

• D.V.M.with 6 years postgraduate experience, including Pathology Residency and PhD
• Minimum of 5 years industry-related experience in toxicologic pathology
• Board Certification by A.C.V.P. or equivalent
• Established research credentials
• Familiarity with current advanced morphologic and other investigative research techniques
• Experience with toxicologic pathology of Laboratory Animals
• Familiarity with spontaneous disease states in Laboratory Animals
• Excellent written and verbal English communication skills
• General knowledge and proficiency with Office Automation Software

For consideration please apply online using the following link: http://allergan.taleo.net/careersection/usa_external/jobdetail.ftl?lang=en&job=090394&src=PA-10420

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